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Tarek MansourReaders, I’m happy to be back here in your inbox with White Pill Issue #27. Hubble spotted a mystery in our space section, and in our engineering and computing section, we have researchers successfully using a laser as a lightning rod. The Investment Index is BACK, and after that we have a gene therapy for deafness, a potential cure for chemo fog, and more in the medicine section. And as always, fun stuff at the end.
San Francisco readers, it was great to meet you on Thursday. Thank you very much for your support and your enthusiasm for the White Pill, it means a lot. It was excellent to hang with you guys.
Ok, let’s get to it.
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Hubble spots a mystery. The Hubble Space Telescope has spotted an intergalactic mystery, something called a Luminous Fast Blue Optical Transient (LFBOT). LFBOTs were first discovered in 2018, are quite rare, and of unknown origin. They're a little like a very powerful supernova, except they brighten and dim far faster, in days instead of weeks or months. This latest find complicates things further, because it's in the void between galaxies, the last place one would expect an energetic event like this to occur. The team working on these findings think it might be “the result of a collision between two neutron stars that were ejected from their host galaxy and had been spiraling toward each other for billions of years.” I look at this as proof that the book of discovery yet remains wide open, so let's keep exploring! Or as Shakespeare would say, "There are more things in Heaven and Earth, Horatio, than are dreamt of in your philosophy." (Universe Today)
The Millennium Falcon rides again! In the 16th White Pill, we told you about a comet reminiscent of the Millennium Falcon. It's back! The comet itself didn't disappear, but the explosive outgassing of dust and debris that formed a shape similar to the famous ship did. Except that it's now done it again and astronomers aren't entirely sure why, though it could be caused by cryovolcanism (an ice volcano). Stay tuned, this comet, imaginatively dubbed Comet 12P, should be easily visible to the naked eye in April 2024. (Spaceweather.com)
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Catching the lightning. Scientists have managed to deflect lighting by almost 200 feet in a real-world test using a powerful laser. While this has been done in a lab before, it’s the first time it worked out in nature. If you use a powerful enough laser, it turns air molecules into a plasma, which is electrically conductive, offering a path of least resistance to lightning from cloud to ground. The problem is creating a pathway that lasts. To achieve this in a useful way, researchers built a laser able to fire 1,000 powerful pulses per second. This successful test opens the door for laser lightning rods that give a far greater area of protection than traditional metal ones. Smart. (Science Alert)
AI predicts earthquakes. Accurately predicting earthquakes before they occur is the holy grail of natural disaster forecasting. But while we have a fairly good understanding of the type and approximate earthquake size an area is vulnerable to, actually predicting them has been impossible. Maybe not for AI though. A team from the University of Texas “tested an AI algorithm that accurately predicted 70 percent of earthquakes a week before they happened,” over seven months in China. It correctly predicted “the location of 14 earthquakes within about 200 miles of where they actually occurred and at almost exactly the calculated strength.” It issued eight false alarms, but only missed one earthquake. (Interesting Engineering)
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The White Pill Investment Index tracks investments in companies developing interesting, exciting, forward-thinking products. Deals are sourced using a combination of Pitchbook and reach outs to each company.
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Gene therapy for deafness. Some estimates have auditory neuropathy, a type of deafness caused by a gene variation that ‘turns off’ the ability of inner hair cells in the ear to communicate with the hearing nerve, affecting up to 10% of children with hearing loss. Typically, the condition is treated with cochlear implants, which are suboptimal in everyday situations where there’s a lot of background noise and things making sound. But a gene therapy has been developed to reverse the effect of this variation, literally replacing the gene by putting the patient under general anesthesia and injecting it into his cochlea, and its first trial just began this month. Pretty cool, could be a game changer — results will be published in February, and trial participants will be monitored for the next five years. (FT)
Faster DNA detection. A new method of DNA detection is about 100x more sensitive than commonly used methods. It's faster too, potentially giving results in minutes instead of hours, days, or months that are typical now. It works by putting the sample in an alternating electric field, then, “we let the DNA dance.” The target DNA will have a specific oscillation frequency in the field that differs from other molecules, including non-target DNA strands. Among other benefits, this could allow for more rapid and easier disease detection, leading to faster treatment and better outcomes. (SciTechDaily)
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The Herculaneum Scrolls, also known as the Villa of the Papyri Scrolls, are a collection of ancient Roman papyri that were carbonized by the eruption of Mount Vesuvius in 79 AD. The carbonization helped to preserve the shape of the scrolls, but it also made them very fragile and difficult to unroll and read. So basically, we don’t know what they say… but we know they say something, because they’re scrolls. Discovered in the 18th century in the ancient town of Herculaneum, near modern-day Naples, they were found in a villa believed to belong to Julius Caesar's father-in-law, Lucius Calpurnius Piso Caesoninus.
But, plot twist, holy s**t, now we do know what they say (partly)!! They say “purple dye” or “cloths of purple” in Greek, which makes sense for scrolls like these, being found at a Roman emperor’s uncle’s house. Purple dye is, apparently, historically significant because it was often associated with royalty or nobility due to its high cost of production in ancient times.
We know what the scrolls say because of the Vesuvius Challenge, a computer science competition where participants were challenged to use machine learning to read the scrolls. Since then, participants have detected ink and words, as well as imaged the words. Really cool. (@natfriedman)
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Touch grass this weekend.
-Brandon Gorrell
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